Cytokeratin 14 (KRT14) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Mouse skin tissue IHC: 25-100 Positive control: Human cervical cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 457-472 amino acids of Human Keratin, type I cytoskeletal 14
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52 kDa
Gene Name	keratin 14
Database Link	NP_000517 Entrez Gene 16664 MouseEntrez Gene 287701 RatEntrez Gene 3861 Human UniProt ID P02533
Background	This gene encodes a member of the keratin family; the most diverse group of intermediate filaments. This gene product; a type I keratin; is usually found as a heterotetramer with two keratin 5 molecules; a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Synonyms	CK14; EBS3; EBS4; K14; NFJ
Reference Data

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