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p57 Kip2 (CDKN1C) Rabbit Polyclonal Antibody
CAT＃: TA323746S
Anti-CDKN1C Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human colorectal cancer Predicted cell location: Nucleus |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 1-14 amino acids of human cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | cyclin-dependent kinase inhibitor 1C |
| Database Link | |
| Background | This gene is imprinted; with preferential expression of the maternal allele. The encoded protein is a tight-binding; strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome; suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. |
| Synonyms | BWCR; BWS; KIP2; p57; p57Kip2; WBS |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Cell cycle |
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