BCOR Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:2000-5000, WB: 1:500-2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 2-189 amino acids of human BCL6 corepressor
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21 kDa
Gene Name	BCL6 corepressor
Database Link	NP_001116855 Entrez Gene 71458 MouseEntrez Gene 317346 RatEntrez Gene 54880 Human UniProt ID Q6W2J9
Background	The protein encoded by this gene was identified as an interacting corepressor of BCL6; a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6; but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein; which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.
Synonyms	ANOP2; MAA2; MCOPS2
Reference Data
Protein Families	Transcription Factors

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