VDAC2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 283-294 amino acids of human voltage-dependent anion channel 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	voltage dependent anion channel 2
Database Link	NP_003366 Entrez Gene 22334 MouseEntrez Gene 83531 RatEntrez Gene 7417 Human UniProt ID P45880
Background	This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1; 2; 12 and 21; and alternative splicing results in multiple transcript variants.?
Synonyms	POR
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other
Protein Pathways	Calcium signaling pathway, Huntington's disease, Parkinson's disease

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.