TOP1MT Rabbit Polyclonal Antibody
CAT#: TA324243
Anti-TOP1MT Rabbit Polyclonal Antibody
Size: 25 ul
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CNY 1,999.00
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CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 15-50 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm, Nucleus |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 151-165 amino acids of human topoisomerase (DNA) I, mitochondrial |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | topoisomerase (DNA) I, mitochondrial |
Database Link | |
Background | This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Synonyms | 2900052H09Rik; mitochondrial; mitochondrial topoisomerase I; topoisomerase (DNA) I |
Reference Data | |
Protein Families | Druggable Genome |
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