Cortactin (CTTN) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human Cortactin around the phosphorylation site of Tyrosine 466
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	85 kDa
Gene Name	cortactin
Database Link	NP_001171669 Entrez Gene 13043 MouseEntrez Gene 60465 RatEntrez Gene 2017 Human UniProt ID Q14247
Background	cortactin a cytoskeletal protein that that is involved in coordinating actin reorganization during cell movement. Localizes at the leading edge of lamellipodia during cell migration. Its amino-terminal acidic domain associates with the Arp2/3 and WASP complex at F-actin branches.
Synonyms	EMS1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Pathogenic Escherichia coli infection, Tight junction

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