Ankyrin brain (ANK2) Mouse Monoclonal Antibody [Clone ID: S105-13]

Specifications

Product Data
Clone Name	S105-13
Applications	WB
Recommend Dilution	IHC: 1:50-1:200, ICC: 1:50-1:200
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide amino acids 203-496 of human Ankyrin-B
Formulation	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ankyrin 2, neuronal
Database Link	NP_001120965 Entrez Gene 109676 MouseEntrez Gene 362036 RatEntrez Gene 287 Human UniProt ID Q01484
Background	Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to thespectrin-actin based membrane skeleton . Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of theplasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membranes.
Synonyms	ANK-2; brank-2; LQT4
Note	Detects ~200kDa. No cross reactivity against Ankyrin-G
Reference Data
Protein Families	Druggable Genome

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