CASK Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CASK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CASK.
Formulation	CASK Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CASK Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calcium/calmodulin dependent serine protein kinase
Database Link	NP_003679 Entrez Gene 12361 MouseEntrez Gene 29647 RatEntrez Gene 8573 Human UniProt ID O14936
Background	CASK Antibody: CASK (Calcium/calmodulin-dependent serine protein kinase), a conserved multi-domain scaffolding protein, belongs to a MAGUK (membrane-associated guanylate kinase homologs) subfamily and is involved in cell junction organization, tumor suppression and signaling. It is characterized by a novel domain structure that consists of a calcium/calmodulin-dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is ubiquitously expressed and significantly greater in brain where it is thought to be involved in signaling at neuronal synapses. CASK interacts with CASKINs and defects in CASK are the cause of mental retardation X-linked CASK-related.
Synonyms	CAGH39; CAMGUK; CMG; FGS4; LIN2; MICPCH; MRXSNA; TNRC8
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Tight junction

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