C11orf2 (VPS51) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fat Free antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human Fat Free.
Formulation	Fat Free Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Fat Free Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	86 kDa
Gene Name	VPS51, GARP complex subunit
Database Link	NP_037397 Entrez Gene 68505 MouseEntrez Gene 100361915 RatEntrez Gene 738 Human UniProt ID Q9UID3
Background	Fat Free Antibody: Fat Free, also known as ANG2, was identified though a yeast two-hybrid screen using VP53. It is thought to be a structural and functional homolog of the yeast protein VPS51, a protein that together with VPS52, VPS53, and VPS54 form the Golgi-associated retrograde protein (GARP) complex that mediates the tethering and fusion of endosome-derived transport carriers to the trans-Golgi network (TGN). Similar to depletion of any of the VPS52, VPS53, or VPS54, depletion of Fat Free using RNAi impairs protein retrieval to the TGN indicating that Fat Free is missing component of the GARP complex in most eukaryotes.
Synonyms	ANG2; ANG3; C11orf2; C11orf3; FFR
Reference Data

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