PPFIA3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	PPFIA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PPFIA3
Formulation	PPFIA3 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	PPFIA3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 131 kDa; Observed: 131 kDa
Gene Name	PTPRF interacting protein alpha 3
Database Link	NP_003651 Entrez Gene 76787 MouseEntrez Gene 140591 RatEntrez Gene 8541 Human UniProt ID O75145
Background	The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development (1). Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones (2).
Synonyms	LPNA3
Reference Data
Protein Families	Druggable Genome

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