LAMTOR1 Rabbit Polyclonal Antibody

CAT#: TA326713

Rabbit Polyclonal LAMTOR1 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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经常一起买 (2)
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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Rabbit polyclonal LAMTOR1 antibody was raised against a 17 amino acid peptide near the amino terminus of human LAMTOR1
Formulation LAMTOR1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification LAMTOR1 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size Predicted: 18 kDa; Observed: 18 kDa
Gene Name late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Background LAMTOR1 is a 161 amino acid membrane protein belonging to the LAMTOR family. It has been identified to interact with and recruit the four Rag GTPases (Rag A-D) to the surface of lysosomes (1). The mTORC1 kinase complex is a critical component in the regulation of cell growth (2). As part of the ragulator complex, LAMTOR1 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids (3). LAMTOR1 may be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes / lysosomes (4).
Synonyms C11orf59; p18; p27RF-Rho; PDRO; Ragulator1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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