RHOC Rabbit Polyclonal Antibody

CAT#: TA326906S

RHOC Rabbit Polyclonal Antibody

Size: 30 ug 100 ul



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热销推荐

CNY 1,100.00


货期*
5 工作日

规格
    • 30 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB 1:500 - 1:2000
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human RHOC
Formulation Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name ras homolog family member C
Background Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI) (1). RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localization allow these three proteins to respond to and act on distinct signaling molecules (2,3).1. DerMardirossian, C. and Bokoch, G.M. (2005) Trends Cell Biol 15, 356-63.2. Wennerberg, K. and Der, C.J. (2004) J Cell Sci 117, 1301-12.3. Wheeler, A.P. and Ridley, A.J. (2004) Exp Cell Res 301, 43-9.
Synonyms ARH9; ARHC; H9; RHOH9
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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