RRM1 Rabbit Polyclonal Antibody

CAT#: TA326954

RRM1 Rabbit Polyclonal Antibody



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热销推荐

CNY 1,999.00

CNY 2,700.00


货期*
2周

规格
    • 100 ul

Product images

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Recombinant protein of human ribonucleotide reductase M1 (RRM1), 20 µg
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Recombinant protein of human ribonucleotide reductase M1 (RRM1), 100 µg
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Specifications

Product Data
Applications ICC/IF, IHC, IP, WB
Recommend Dilution WB 1:500 - 1:2000;IF 1:50- 1:200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human RRM1
Formulation Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name ribonucleotide reductase catalytic subunit M1
Background Ribonucleotide reductase catalyzes the rate-limiting step in the synthesis of deoxynucleotide triphosphates (dNTPs). The regulatory M1 subunit (RRM1) is present throughout the cell division cycle, but downregulated in quiescent cells . Research studies have demonstrated that RRM1 is involved in carcinogenesis and tumor progression, and its expression is correlated with resistance to chemotherapy in non-small cell lung cancer .
Synonyms R1; RIR1; RR1
Reference Data
Protein Families Druggable Genome
Protein Pathways Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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