CD247 Mouse Monoclonal Antibody [Clone ID: 6B10.2]

Specifications

Product Data
Clone Name	6B10.2
Applications	WB
Recommend Dilution	WB, ICFC
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human TCR zeta chain aa38-54
Formulation	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CD247 molecule
Database Link	NP_932170 Entrez Gene 919 Human UniProt ID P20963
Background	The invariant TCR zeta chain is a member of the CD3 complex associated with the clonotypic alpha/beta TCR hetrodimer. The disulfide-linked TCRzeta homodimers transmit signals following TCR ligation. Loss of TCR zeta expression has been reported in a diverse range of disease states, including autoimmune diseases, many neoplastic conditions and chronic infections, such as tuberculosis and leprosy.
Synonyms	CD3-ZETA; CD3H; CD3Q; CD3Z; IMD25; T3Z; TCRZ
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway

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