Usp21 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Usp21 antibody is synthetic peptide directed towards the N-terminal region of Mouse Usp21. Synthetic peptide located within the following region: PLPPRPGPPDERLKKLELGRGRTSGSRPRGPLRADHGVPLPGSPPPAVAL
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	62 kDa
Gene Name	ubiquitin specific peptidase 21
Database Link	NP_038947 Entrez Gene 30941 Mouse UniProt ID Q9QZL6
Background	Usp21 deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Usp21 regulates gene expression via histone H2A deubiquitination. It is also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
Synonyms	MGC3394; USP16; USP23
Note	Immunogen Sequence Homology: Rat: 100%; Human: 100%; Pig: 93%; Mouse: 93%; Rabbit: 93%; Guinea pig: 93%; Dog: 86%; Horse: 86%; Bovine: 86%
Reference Data

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