NG2 (CSPG4) Mouse Monoclonal Antibody [Clone ID: LHM 2]
CAT#: TA336295
Mouse Monoclonal NG2/MCSP Antibody (LHM 2)
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CNY 5,521.00
货期*
5周
规格
经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | LHM 2 |
Applications | FC, ICC/IF, IHC, IP, WB |
Recommend Dilution | Flow (Cell Surface): 1 - 2.5 ug/mL, Immunoprecipitation: 1:10 - 1:100, Flow Cytometry: 1 ug/ml, Knockout Validated, Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:100, Western Blot: 1:1000, Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry-Frozen: 1:200 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | A 375P cells crude extract |
Formulation | PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Protein G purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | chondroitin sulfate proteoglycan 4 |
Database Link | |
Background | NG2 (Neuron Glial Antigen 2), also known as MCSP, and CSPG4 is a chondroitin surface proteoglycan. Chondroitin surface proteoglycans play a role in stabilizing cell-substratum interactions during early events of cell spreading. At large, proteoglycans are important for cell proliferation and migration, and may act as signal transducers through C-terminal cytoplasmic binding to scaffolding or signaling proteins. The NG2 glycoprotein is a type I membrane protein expressed in the developing and adult central nervous system (CNS) by subpopulations of glia including oligodendroglial precursor cells (OPCs), and in the developing CNS additionally by pericytes. NG2 is located at the apical cell membrane, however it has also been shown to localize to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Research has found that NG2 may inhibit neuronal growth (PMC1571583), and also acts as a proapoptotic receptor. |
Synonyms | HMW-MAA; MCSP; MCSPG; MEL-CSPG; MSK16; NG2 |
Note | This NG2 Antibody (LHM 2) is useful for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry on both frozen and paraffin-embedded sections, Immunoprecipitation and Western Blot. In WB, a band can be seen at ~300 kDa. |
Reference Data | |
Protein Families | Transmembrane |
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