PMS2 Mouse Monoclonal Antibody [Clone ID: 163C1251]

Specifications

Product Data
Clone Name	163C1251
Applications	CyTOF-ready, FC, WB
Recommend Dilution	Flow Cytometry: 1ug per 10^6 cells, Western Blot: 1-2 ug/ml, Immunohistochemistry: 2-5ug/ml, Immunohistochemistry-Paraffin: 2-5ug/ml, CyTOF-ready
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2; GenBank No. NP_000526.1.
Formulation	PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	PMS1 homolog 2, mismatch repair system component
Database Link	NP_000526 Entrez Gene 18861 MouseEntrez Gene 5395 Human UniProt ID P54278
Background	PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.
Synonyms	HNPCC4; PMS2CL; PMSL2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Mismatch repair

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