AKR1B1 Mouse Monoclonal Antibody [Clone ID: 4G9-B6-F6]

Specifications

Product Data
Clone Name	4G9-B6-F6
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for AKR1B1 antibody: purified recombinant human AKR1B1 protein fragments expressed in E.coli.
Formulation	PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36 kDa
Gene Name	aldo-keto reductase family 1, member B1 (aldose reductase)
Database Link	NP_001619 Entrez Gene 24192 RatEntrez Gene 231 Human UniProt ID P15121
Background	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. (provided by RefSeq, Feb 2009)
Synonyms	ADR; ALDR1; ALR2; AR
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Pyruvate metabolism

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