CDK1 Mouse Monoclonal Antibody [Clone ID: 3B9-F8-B12]

Specifications

Product Data
Clone Name	3B9-F8-B12
Applications	IF, WB
Recommend Dilution	WB: 1:100, IF: 1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for CDK1 antibody: purified recombinant human CDC2/CDK1 protein fragments expressed in E.coli.
Formulation	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34 kDa
Gene Name	cyclin-dependent kinase 1
Database Link	NP_001124301 Entrez Gene 983 Human UniProt ID P06493
Background	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	CDC28A; CDK1; DKFZp686L20222; MGC111195
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways	Cell cycle, Gap junction, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation

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