Hexokinase II (HK2) Mouse Monoclonal Antibody [Clone ID: 3B9-F8-F10]

Specifications

Product Data
Clone Name	3B9-F8-F10
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for HK2 antibody: purified recombinant human Hexokinase II protein fragments expressed in E.coli.
Formulation	PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	102 kDa
Gene Name	hexokinase 2
Database Link	NP_000180 Entrez Gene 3099 Human UniProt ID P52789
Background	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Synonyms	HKII; HXK2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus

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