KMT2B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA (1:200 ?? 1:2,000) ; Western blotting (1:500)
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Mll2 antibody: mouse Mll2 (Myeloid/lymphoid or mixed-lineage leukemia protein 2), using two KLH-conjugated synthetic peptides containing an amino acid sequence from the central and from the N-terminal part of the protein, respective
Concentration	lot specific
Purification	Whole antiserum from rabbit containing 0.05% azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	lysine methyltransferase 2B
Database Link	NP_055542 Entrez Gene 75410 Mouse UniProt ID Q9UMN6
Background	Mll2 (UniProtKB/Swiss-Prot entry Q9UMN6) plays a role in H3K4 methylation and may therefore act as a transciptional regulator. Mll2 is essential for embryonic development and may also be important for hematopiesis. Further, Mll2 shows an elevated expression in solid tumor cell lines, and may be involved in cancer.
Synonyms	CXXC10; HRX2; MLL1B; MLL2; MLL4; TRX2; WBP-7; WBP7
Reference Data
Protein Families	Druggable Genome

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