TIF1 alpha (TRIM24) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-TRIM24 Antibody: A synthesized peptide derived from human TRIM24
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	117 kDa
Gene Name	tripartite motif containing 24
Database Link	NP_003843 Entrez Gene 21848 MouseEntrez Gene 8805 Human UniProt ID O15164
Background	TRIM24 an atypical protein kinase that functions as a transcriptional coactivator. Originally identified as a mammalian protein that enhances the AF-2 activity of the retinoid X receptor (RXR) in a yeast genetic screen. Binds to nuclear receptors in an agonist and AF2-activating domain (AF2-AD) dependent manner. Binding to the agonist-nuclear receptor complex induces its own hyperphosphorylation as well as the phosphorylation of TFIIEa, TAFII28, and TAFII55.
Synonyms	hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA
Note	TRIM24 antibody detects endogenous levels of total TRIM24
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transcription Factors

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