PON2 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 2-4 ug/ml
Reactivity	Human, Mouse, Rat, Pig, Dog, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	The immunogen for Anti-PON2 Antibody: Peptide with sequence C-ERLLALRNRLKAS, from the internal region of the protein sequence according to NP_000296.2; NP_001018171.1.
Formulation	Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	paraoxonase 2
Database Link	NP_000296 Entrez Gene 296851 RatEntrez Gene 330260 MouseEntrez Gene 403855 DogEntrez Gene 5445 Human UniProt ID Q15165
Background	This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms	A-esterase 2; aromatic esterase 2; arylesterase 2; paraoxonase 2; paraoxonase nirs; serum aryldialkylphosphatase 2; serum paraoxonase
Note	This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.