Neuroligin 2 (NLGN2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	NLGN2 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 92, 99 kDa; Observed: 80, 97 kDa
Gene Name	neuroligin 2
Database Link	NP_065846 Entrez Gene 57555 Human UniProt ID Q8NFZ4
Background	Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5).
Synonyms	DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.