GLIS2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	GLIS2 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 58 kDa; Observed: 60 kDa
Gene Name	GLIS family zinc finger 2
Database Link	NP_115964 Entrez Gene 84662 Human UniProt ID Q9BZE0
Background	GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).
Synonyms	KIRRE; MRD4; NEPH2; PRO4502
Reference Data

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