VTI1A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	VTI1a antibody was raised against a 19 amino acid peptide near the center of human VTI1a.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	VTI1a antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 24, 27 kDa; Observed: 26 kDa
Gene Name	vesicle transport through interaction with t-SNAREs 1A
Database Link	NP_660207 Entrez Gene 53611 MouseEntrez Gene 65277 RatEntrez Gene 143187 Human UniProt ID Q96AJ9
Background	Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). VTI1a mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane and promotes fusion of the lipid bilayers (4). VTI1a may be concerned with increased secretion of cytokines associated with cellular senescence (5).
Synonyms	MMDS3; MVti1; Vti1-rp2; VTI1RP2
Reference Data
Protein Families	Transmembrane
Protein Pathways	SNARE interactions in vesicular transport

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.