CHAC1 Rabbit Polyclonal Antibody
CAT#: TA349800
Rabbit Polyclonal Anti-CHAC1 Antibody
Size: 25 ul
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
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CNY 9,998.00
CNY 3,080.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human CHAC1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | ChaC glutathione specific gamma-glutamylcyclotransferase 1 |
Database Link | |
Background | CHAC1 (ChaC, cation transport regulator homolog 1 (E. coli)) is a 264 amino acid cytoplasmic protein that belongs to the ChaC family. Induced by chemical activators of the unfolded protein response (UPR) pathway, including DTT, tunicamycin and thapsigargin, CHAC1 is a pro-apoptotic member of this pathway and may mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Overexpression of CHAC1 may lead to an increase in apoptosis, while suppression of CHAC1 results in subdued apoptosis. |
Synonyms | MGC4504 |
Reference Data |
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