CSMD1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CSMD1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CUB and Sushi multiple domains 1
Database Link	NP_150094 Entrez Gene 94109 MouseEntrez Gene 64478 Human UniProt ID Q96PZ7
Background	CSMD1 CUB and Sushi multiple domains 1 is a protein that in humans is encoded by the CSMD1gene. It is a potential tumour suppressor, the deletion of which may result in head and neck carcinomas behaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.
Synonyms	PPP1R24
Reference Data
Protein Families	Druggable Genome, Transmembrane

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