LASS4 (CERS4) Rabbit Polyclonal Antibody
CAT#: TA351343
Rabbit Polyclonal Anti-CERS4 Antibody
Size: 25 ul
Need it in bulk or conjugated?
Get a free quote
CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 9,998.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Human fetal liver tissue, HT-29 and HUVEC cells, MCF-7 cells and human hepatocellsular carcinoma tissue IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CERS4 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 46 kDa |
Gene Name | ceramide synthase 4 |
Database Link | |
Background | The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis. |
Synonyms | LASS4; Trh1 |
Reference Data | |
Protein Families | Transcription Factors, Transmembrane |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |