MCG10 (PCBP4) Rabbit Polyclonal Antibody
CAT#: TA351388S
Rabbit Polyclonal Anti-PCBP4 Antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 200-1000 WB positive control: Mouse kidney tissue |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human PCBP4 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 41 kDa |
Gene Name | poly(rC) binding protein 4 |
Database Link | |
Background | This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. |
Synonyms | CBP; LIP4; MCG10 |
Reference Data |
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