Ifng Mouse Monoclonal Antibody [Clone ID: DB-2]

Specifications

Product Data
Clone Name	DB-2
Recommend Dilution	Neutralization assay, Western Blot
Reactivity	Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	IFN-gamma
Formulation	Prior to lyophilization: 0.5 ml PBS + 125 mM trehalose.
Concentration	lot specific
Purification	Ion exchange chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	17.9 kDa
Gene Name	interferon gamma
Database Link	NP_620235 Entrez Gene 15978 MouseEntrez Gene 25712 Rat UniProt ID P01581
Background	The mouse anti-rat IFN-? monoclonal antibody (clone DB-2) is, in terms of reactivity, very similair to the DB-1 antibody (cat. no. CT032). Whereas the DB-1 antibody is a mouse monoclonal antibody of the IgG1 subtype, clone DB-2 is an IgA subtype. The DB-2 antibody has shown not to bind with rodent IFN-a1 and -β or to human IFNs. The antibody effectively neutralizes both rat and mouse IFN-? in vitro and in vivo. (Van der Meide P.H. et al. 1989 and Issekutz T.B. et al. 1988). Further, the DB-2 antibody is active in Western Blot analysis (Van der Meide P.H. et al. 1986).
Synonyms	IFG; IFI; IFN-gamma
Reference Data

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