SOX4 Rabbit Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the c-terminus (from 720AA-755aa) of human sox6 protein. This sequence is identical in human, mouse, rat, bovine, canis and chicken species.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SRY-box 4
Database Link	NP_003098 Entrez Gene 6659 Human UniProt ID Q06945
Background	SOX6 gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. SOX6 protein is a transcriptional activator that is specifically expressed in the developing central nervous system and in the early stages of chondrogenesis in mouse embryos. It is found to be essential to both cartilage formation/chondrogenesis and obesity-related insulin resistance. The SOX6 protein is also detected in glioma patient sera and brain tissues.
Synonyms	EVI16
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors

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