SMN1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to C-terminus of human SMN.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	35 kDa
Gene Name	survival of motor neuron 1, telomeric
Database Link	NP_000335 Entrez Gene 6606 Human UniProt ID Q16637
Background	The survival motor neuron (SMN) protein is the protein product of the spinal muscular atrophy (SMA) disease. SMN gene is the SMA determining gene. In humans, there are two nearly identical copies of the survival of motor neuron genes (SMN1 and SMN2), whereas other eukaryotic species have only one copy of the SMN gene. SMN is expressed ubiquitously and is a core component of a self-assembling multiprotein complex. The SMN complex, consisting of SMN and Gemin proteins (Gemin2, -3, -4, -5, -6, -7 and –8), in which SMN-Gemin2 complex plays an essential role in the assembly and regeneration of small nuclear ribonucleoproteins (snRNPs) and spliceosomes.
Synonyms	BCD541; GEMIN1; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMNT; T-BCD541; TDRD16A
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.