BCMA (TNFRSF17) Rabbit Monoclonal Antibody [Clone ID: DM16]

CAT#: TA355176

BCMA bispecific antibody, clone DM16



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CNY 6,178.00


货期*
2周

规格
    • 100 ug

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Specifications

Product Data
Clone Name DM16
Applications FC, FN
Recommend Dilution Flow Cyt  1/100; MMTumor cell killing
Reactivity Human
Host Rabbit
Clonality Monoclonal
Immunogen Recombinant human BCMA (Met1-Ala54) (TP723924) produced by using human HEK293 cells
Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Preservative: 0.1% Procline 300
Reconstitution Method Reconstitute with deionized water
Purification Purified from cell culture supernatant by affinity chromatography
Conjugation Unconjugated
Storage Condition Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Predicted Protein Size 20kDa
Gene Name tumor necrosis factor receptor superfamily member 17
Background BiTE bispecific antibody is an Engineered fusion protein constructed from two single-chain variable fragments (scFvs) of different monoclonal antibodies. One of the scFvs will be constructed from an anti-CD3 monoclonal antibody, and the other scFv fragment which linked by a linker region will be made from an anti-Tumor cell specific monoclonal antibody.The B-cell maturation protein (BCMA or BCM) is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Synonyms BCM; BCMA; CD269
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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