CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: MTB1]

Specifications

Product Data
Clone Name	MTB1
Applications	IHC
Recommend Dilution	1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant fusion protein corresponding to the full external domain of the human CD1a molecule
Specificity	Human CD1a molecule. Some evidence of crossreactivity with CD1b shown by reactivity with small focal groups of lymphocytes outside the germinal centers of tonsil.
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	CD1a molecule
Database Link	Entrez Gene 909 Human UniProt ID P06126
Background	CD1a is a protein of 43 to 49 kD expressed on dendritic cells and cortical thymocytes. CD1a antigen expression has been shown to be useful in differentiating Langerhans cells, powerful antigen presenting cells present in skin and epithelia, from interdigitating cells. Immunohistochemical studies for CD1a antigen have reported a reduction in epidermal Langerhans cells in graft versus host disease and the participation of CD1a antigen-positive dendritic cells in atherosclerotic lesion formation and asthmatic inflammation.
Synonyms	CD1; FCB6; HTA1; R4; T6
Reference Data

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