TMEM16A (ANO1) Mouse Monoclonal Antibody [Clone ID: K9]

Specifications

Product Data
Clone Name	K9
Applications	IHC
Recommend Dilution	1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to part of the C-terminus of the cytoplasmic domain of the human DOG-1 molecule
Specificity	Human DOG-1
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	anoctamin 1
Database Link	Entrez Gene 55107 Human UniProt ID Q5XXA6
Background	DOG-1, a 986 amino acid protein of unknown function, is expressed predominantly on the plasma membrane of gastrointestinal stromal tumors (GISTs) and is rarely expressed in other soft tissue tumors, which, due to appearance, can be confused with GISTs. Reactivity for DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express KIT antigen.
Synonyms	DOG1; FLJ10261; ORAOV2; TAOS2; TMEM16A
Reference Data

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