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Bak (BAK1) Rabbit Polyclonal Antibody
CNY 4,628.00
货期*
2周
规格
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Specifications
| Product Data | |
| Applications | WB |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Specificity | Expected reactivity: Horse, Human Homology: Horse: 80%; Human: 100% |
| Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage Condition | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Predicted Protein Size | 23kDa |
| Gene Name | BCL2 antagonist/killer 1 |
| Database Link | |
| Background | BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
| Synonyms | BAK; BAK-LIKE; Bcl2-L-7; BCL2L7; CDN1; MGC3887; MGC117255 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transmembrane |
Documents
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