B4GALNT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of human B4GALNT1
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat Homology: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	59kDa
Gene Name	beta-1,4-N-acetyl-galactosaminyltransferase 1
Database Link	NP_001469 Entrez Gene 2583 Human UniProt ID Q00973
Background	GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. B4GALNT1(GalNAc-T) catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively.
Synonyms	(N-acetylneuraminyl)-galactosylglucosylceramide; beta1,4GalNAc-T; beta1-4GalNAc-T; GALGT; GalNAc-T; GALNACT; SIAT2; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuram
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Glycosphingolipid biosynthesis - ganglio series, Metabolic pathways

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