Laminin alpha 4 (LAMA4) Rabbit Polyclonal Antibody

CAT#: TA357174

LAMA4 Antibody - C-terminal region



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CNY 4,628.00


货期*
2周

规格
    • 50 ug

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经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Transient overexpression lysate of laminin, alpha 4 (LAMA4), transcript variant 1
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Applications WB
Reactivity Human
Host Rabbit
Clonality Polyclonal
Specificity Expected reactivity: Human
Homology: Human: 100%
Formulation Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Note that this product is shipped as lyophilized powder to China customers.
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size 10kDa
Gene Name laminin subunit alpha 4
Background Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature.
Synonyms DKFZp686D23145; LAMA3; LAMA4*-1
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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