H3f3a Rabbit Polyclonal Antibody

CAT#: TA357782

H3f3a Antibody - N-terminal region



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CNY 5,250.00


货期*
6周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Specificity Expected reactivity: Dog, Pig, Rat, Zebrafish
Homology: Dog: 100%; Pig: 100%; Rat: 100%; Zebrafish: 100%
Formulation Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size 15kDa
Gene Name H3 histone, family 3A
Background H3f3a is a variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. H3f3a constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. H3f3a is deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms H3.3A; H3.3B; H3F3; MGC87782; MGC87783; OTTHUMP00000035619; OTTHUMP00000035621
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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