Osteocalcin (BGLAP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Osteocalcin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Tyr-Leu-Tyr-Gln-Trp-leu-Gly-Ala-Pro-Val-Pro-Tyr- Pro-Asp-Pro-Leu-Glu-Pro-Arg-Arg-Glu-Val-Cys-Glu-Leu-Asn-Pro-Asp- Cys-Asp-OH coupled to a carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	bone gamma-carboxyglutamate protein
Database Link	Entrez Gene 632 Human UniProt ID P84351
Background	Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a 49-amino acid non-collagenous protein hormone found in bone and dentin, first identified as a calcium-binding protein in chick bone. Because osteocalcin has gla domains, its synthesis is vitamin K dependent. Osteocalcin is secreted solely by osteoblasts and thought to play a role in the body's metabolic regulation. In its carboxylated form it binds calcium directly and thus concentrates in bone. This antibody was generated by immunization of rabbits with Osteocalcin coupled to a carrier protein.
Synonyms	BGP; OC; osteocalcin; PMF1
Reference Data

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