Calcitonin (CALCA) Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against α-CGRP. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu- Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val- Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2, (Disulfide bond) coupled to carrier protein.
Formulation	This polyclonal antibody is supplied as a lyophilized powder. The powder should be rehydrated with 50ml of RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4° - 8°C. This should ensure antibody stability for approximately one month.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	calcitonin related polypeptide alpha
Database Link	Entrez Gene 796 Human UniProt ID P06881
Background	α-Calcitonin Gene-Related Peptide (α-CGRP) is a regulatory neuropeptide of 37 amino acids and is formed by the alternative splicing of the calcitonin / CGRP gene located on chromosome 11. It is widely distributed in both the peripheral and central nervous system, predominantly in cell bodies of the dorsal root ganglion (DRG) and it is known to be a potent vasodilator with inotropic and chronotropic effects. This antibody was generated by immunization of guinea pigs with α-Calcitonin Gene- Related Peptide coupled to a carrier protein.
Synonyms	CALC1; CGRP; CGRP-I; CGRP1; CT; katacalcin; KC; MGC126648; PCT; Procalcitonin
Reference Data

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