IL24 Rabbit Polyclonal Antibody
CAT#: TA368249S
IL24 rabbit polyclonal antibody
Size: 100 ul
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CNY 800.00
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Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 30-150 Positive control: Human cervical cancer Predicted cell location: Cytoplasm or Nucleus |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human IL24 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Gene Name | interleukin 24 |
Database Link | |
Background | This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Synonyms | C49A; FISP; IL-24; IL10B; MDA-7; MDA7; Mob-5; ST16 |
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