ATG5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human ATG5
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	autophagy related 5
Database Link	Entrez Gene 9474 Human UniProt ID Q9H1Y0
Background	Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is an E3 ubiquitinligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
Synonyms	APG5; APG5-LIKE; APG5L; ASP; hAPG5; OTTHUMP00000017824
Reference Data

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