DENND1B Rabbit Polyclonal Antibody
CAT#: TA370090
DENND1B rabbit polyclonal antibody
Size: 25 ul
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 500-2000 WB positive control: Human fetal brain tissue and mouse brain tissue lysates |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human DENND1B |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 86 kDa |
Gene Name | DENN domain containing 1B |
Database Link | |
Background | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery. |
Synonyms | C1orf218; DKFZp547O0715; FAM31B; FLJ20054; FLJ21179; FLJ33888; MGC27044; MGC103810 |
Reference Data |
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