EGLN1 Rabbit Polyclonal Antibody

CAT#: TA375764

EGLN1/EGLN2 Rabbit polyclonal Antibody



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB,1:500 - 1:2000
Reactivity Human
Modifications Unmodified
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide of human EGLN1/EGLN2
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 36kDa/43kDa/46kDa/40kDa
Gene Name egl-9 family hypoxia inducible factor 1
Background The proteins encoded by EGLN1/EGLN2 gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex.
Synonyms C1orf12; DKFZp761F179; ECYT3; HIF-PH2; HIFPH2; HPH-2; HPH2; PHD2; SM-20; SM20; ZMYND6
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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