PDGF Receptor beta (PDGFRB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, WB
Recommend Dilution	WB,1:500 - 1:1000 IHC,1:20 - 1:50 IF,1:20 - 1:50
Reactivity	Human, Mouse, Rat
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic Peptide of human PDGFRB
Formulation	Buffer: PBS with 0.02% sodium azide,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 4℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,pH7.3.
Predicted Protein Size	37kDa/123kDa
Gene Name	platelet derived growth factor receptor beta
Database Link	Entrez Gene 5159 Human UniProt ID P09619
Background	This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Synonyms	CD140b; JTK12; PDGF-R-beta; PDGFR; PDGFR1
Reference Data

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