APPL (APPL1) Rabbit Monoclonal Antibody [Clone ID: R05-8D5]

Specifications

Product Data
Clone Name	R05-8D5
Applications	IHC, WB
Recommend Dilution	WB: 1/1000-1/5000 IHC: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human APPL
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 80 kDa; Observed MW: 80 kDa
Gene Name	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Database Link	Entrez Gene 26060 Human UniProt ID Q9UKG1
Background	Swiss-Prot Acc.Q9UKG1.Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.
Synonyms	APPL; Dip13-alpha; DIP13A; DIP13alpha; KIAA1428
Reference Data

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