Caspase 3 (CASP3) Rabbit Monoclonal Antibody [Clone ID: R04-5C8]
CAT#: TA383877S
Cleaved-Caspase 3 p17 Rabbit monoclonal Antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | R04-5C8 |
Applications | WB |
Recommend Dilution | WB: 1/1000 |
Reactivity | Mouse, Human, Rat |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of mouse Caspase-3 (Cleaved) |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | Calculated MW: 32 kDa; Observed MW: 32,17 kDa |
Gene Name | caspase 3 |
Database Link | |
Background | Swiss-Prot Acc.P70677.Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage . Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. |
Synonyms | apopain; CASP-3; CPP-32; CPP32; CPP32B; procaspase3; SCA-1; Yama |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |