p27 KIP 1 (CDKN1B) Rabbit Monoclonal Antibody [Clone ID: R09-6C3]

CAT#: TA383979S

p27 Kip 1 Rabbit monoclonal Antibody

Size: 20 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 20 ul

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经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
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Specifications

Product Data
Clone Name R09-6C3
Applications IHC, IP, WB
Recommend Dilution WB: 1/1000
IHC: 1/20
IP: 1/20
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide of human p27 KIP 1
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size Calculated MW: 22 kDa; Observed MW: 27 kDa
Gene Name cyclin-dependent kinase inhibitor 1B
Background Swiss-Prot Acc.P46527.Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA (PubMed:28666995). Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Synonyms CDKN4; KIP1; MEN1B; MEN4; P27KIP1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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